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- *********************************************************
- * Neuraxin and MAP1B proteins repeated region signature *
- *********************************************************
-
- MAP1B [1], and neuraxin [2] are neuronal microtubules binding proteins. Both
- proteins contain a region that consists of 12 tandem repeats of a 17 residues
- motif.
-
- The pattern we developed to detect this repeated region corresponds to the
- N-terminal ten residues of the repeated region.
-
- -Consensus pattern: [STAGDN]-Y-x-Y-E-x(2)-[DE]-[KR]-[STAGCI]
- -Sequences known to belong to this class detected by the pattern: ALL; this
- pattern detects 8 out of the 12 copies of the repeated region.
- -Other sequence(s) detected in SWISS-PROT: 4 other proteins; but in all cases
- the pattern is only found once.
-
- -Expert(s) to contact by email: Matus A.
- matus@fmi.ch
-
- -Last update: June 1994 / Text revised.
-
- [ 1] Noble M., Lewis S.A., Cowan N.J.
- J. Cell Biol. 109:3367-3376(1989).
- [ 2] Rienitz A., Grenningloh G., Hermans-Borgmeyer I., Kirsch J.,
- Littauer U.Z., Prior P., Gundelfinger E.D., Schmitt B., Betz H.
- EMBO J. 8:2879-2888(1989).
-